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Cuproptosis may collaborate with CD8 + T cells by inducing innate DAMPs that enhance T cell recruitment

Mutations in the superoxide dismutase enzyme (which stabilizes superoxide radicals and is implicated in the pathology of certain kinds of ALS) can decrease its affinity for zinc and cause it to become toxic to motor neurons

Glutathione is generally well tolerated, but in some people, it can cause mild gastrointestinal distress and allergic reactions if given in very high doses or by way of IV use

These enzymes conjugate toxins with glutathione, facilitating their excretion from the body [28]